Wednesday, November 5, 2014

Magnolol Description


CAS Number:528-43-8
Purity:98%
Molecular Weight:266.3
Molecular Formula:C18H18O2
Magnolol is a bioactive admixture abandoned from the case of M. officinalis that has been acclimated in Asian acceptable anesthetic for the analysis of anxiety, beddy-bye disorders, and allergic diseases. Magnolol can actuate cannabinoid (CB) receptors, behaving as a fractional agonist with selectivity for the borderline CB2 subtype (EC50 = 3.28 μM; Ki = 1.44 μM) against axial CB1 (EC50 = 18.3 μM; Ki = 3.15 μM).

It is a bioactive admixture begin in the case of the Houpu magnolia (Magnolia officinalis) or in M. grandiflora. The admixture exists at the akin of a few percent in the case of breed of magnolia, the extracts of which accept been acclimated in acceptable Chinese and Japanese medicine. In accession to magnolol, accompanying lignans action in the extracts including honokiol, which is an isomer of magnolol.

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