Influenza a virus (state-run Influenza a virus get) is a common Flu virus, the Influenza virus mutates, most easily of Influenza a virus subtype are people to be "Bird Flu", avian Influenza (Bird Flu) is an acute infectious disease caused by avian Influenza virus and can infect humans, the symptoms of infection after mainly characterized by high fever, cough, runny nose, muscle pain, etc., most associated with severe pneumonia and severe heart failure, kidney and other organs lead to death, the case fatality rate is very high. The disease can be through the digestive tract, respiratory tract, skin lesions, and spreading of conjunctiva, etc, the personnel and the traffic is an important factor to spread the disease.
Influenza virus is divided into three type a, b, c, a/h1n1 flu virus mutates, most easily is an influenza pandemic influenza a virus subtype a new subtype or old again. Surface antigen of influenza a/h1n1 virus will often small variation, the mutation is known as "gone with the wind" (drift), figuratively speaking, "gone with the wind" is that a virus through tiny changes in camouflage themselves, so as to achieve the aim of avoiding the body's immune system to recognize. Influenza a virus "gone with the wind" is the result of the annual flu strains may be different, people need to influenza vaccination every year for prevention. "Move" (shift) refers to the a/h1n1 flu virus mutates, cause a kind of new virus subtype "". Because almost no antibodies against the new virus in the human body, so the "move" often leads to the result of the global outbreak of influenza. Influenza viruses often depend on viral protein parts with the combination of a particular protein in the human body to enter the body, because by the combination of the influenza virus can inhibit human natural defense system itself to virus infection, pave the way for virus effectively in the body copy.
The flu virus is divided into a, b, c three type. Influenza a virus based on the H and N antigen, is divided into many subtypes, H can be divided into 15 subtypes (H1 - H15), 9 of N subtypes (N1 ~ N9). Only H1N1, H2N2, H3N2 mainly infect humans, many other subtypes of natural hosts a variety of birds and animals. One of the most harmful to birds for the H5 and H7 and H9 subtype strains. Under normal circumstances, the bird flu virus won't animals infected birds and pigs. But Hong Kong in 1997 was first reported in 18 cases of H5N1 human bird flu infections, including six deaths, caused wide attention around the world. After 1997, the world has happened a few times of avian influenza virus infection in men's event. Has the highly pathogenic H5N1, H7N7, H9N2, such as bird flu virus, once the change and the spread of human ability, can cause human bird flu epidemic, heralding the bird flu virus has great potential threat to mankind.
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