Aflatoxicol Ⅰ occurs as colourless crystal with the melting point 224～226℃. It is soluble in benzene, hexane, slightly soluble in water. It is used as experiment carcinogen.This product shall be sealed to preserve at 0℃.
CAS: 99751-62-9
Molecular Formula: C17H14O6
Formula Weight: 314.29
Application:
1. Aflatoxicol M1 can also be produced from aflatoxin M1 by a reductase present in rabbit liver cytosol, a reaction analogous to the reduction of aflatoxin B1 to aflatoxicol.
2. Using dog liver microsomal preparations, we have isolated and identified a new metabolite of aflatoxicol, aflatoxicol M1; this metabolic transformation is analogous to the conversion of aflatoxin B1 to aflatoxin M1.
3. In addition, aflatoxicol M1 can be oxidized to aflatoxin M1 by a carbon monoxide-insensitive dehydrogenase activity associated with human liver microsomes, a reaction analogous to the production of aflatoxin B1 from aflatoxicol by this fraction.
4. The significance of this new aflatoxin metabolite and the possibility that it may be biologically active are discussed.
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