Monday, December 26, 2011

Andilesin A-Secondary Metabolites

Andilesin A is a C25 polyisoprenoid from Aspergillus sp. X-Ray crystallographic and spectroscopical conclusion of the anatomical structure. The origins of all the oxygen atoms in andilesin A (1) have constituted compulsive along judging analyses with [1-13C, 18O2]acetate, 18O2, and ethyl 3,5-dimethylorsellinate doubly-labelled with 13C and 18O at the carbonyl group and at C-6.
Emericella venezuelensis is a new species, differing from two other species with stellate ascospores, E. variecolor and atomic number 99. pluriseminata, away trilateral flap during the convex sides of the ascospores, and further from E. variecolor by bringing on an Aspergillus anamorph entirely during bizarre increment spiritualists. The ternary species also differ in their profiles of extrolites (secondary metabolites).
The structure of a previously reported C25 polyisoprenoid, ‘dihydroandibenin,’ a metabolite of Aspergillus species, has been elucidated by X-ray and c.d. analysis. The effects suggest a biosynthetic pathway in which andilesin A(1) is dehydrated to give andilesin B (2) which is then reduced to andilesin C (3).

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